Product Description
Overview
This medicine is used to help slow or stop the growth of certain cancer cells. It is part of a class of “targeted therapy” drugs — medicines designed to work on specific processes inside cells that become abnormal in cancer.
How It Works
The medicine works by blocking two specific proteins (called CDK4 and CDK6) that help cells divide and multiply. By inhibiting these proteins, it prevents cancer cells from moving through one of their growth checkpoints — so the cells stop dividing, which helps slow down or stop the spread of cancer.
Common Uses
- Treatment of certain hormone-receptor positive, HER2-negative advanced or metastatic breast cancers.
- Often used in combination with hormone therapies (for example, aromatase inhibitors or similar drugs) to increase effectiveness.
Key Benefits
- Helps to slow or stop cancer cell growth and spread.
- Can extend the time during which the cancer remains stable or under control.
- Offers a targeted treatment option, which may have different effects compared to traditional chemotherapy.
Safety & Precautions
- Should be taken exactly as prescribed (often as a daily oral capsule, with food).
- Because it works by slowing cell division, it may affect healthy cells too — especially those that normally divide often (e.g. bone marrow cells), which may lower immunity.
- It is important to follow any instructions regarding combination with other medicines or restrictions (e.g. certain drugs or foods that might interfere with its action).
Scientific Literature (External Links)
- Palbociclib: A Novel Cyclin-Dependent Kinase Inhibitor for… — explains how this drug stops cancer cell growth by blocking CDK4/6.
- Palbociclib and Letrozole in Advanced Breast Cancer (Phase 3 clinical study) — describes how palbociclib, when combined with hormone therapy, helps patients with advanced hormone-receptor positive breast cancer.
- Palbociclib: an evidence-based review of its potential in the treatment… — reviews the cell-cycle mechanisms and rationale for using palbociclib in cancer therapy.
These details are compiled from publicly available scientific sources. MYMEDS.MD is not liable for clinical interpretation. Please consult a licensed medical practitioner for personalised guidance.